Peer-reviewed veterinary case report
Septicemic salmonellosis and suspected phenylbutazone toxicosis in an aged pony.
- Journal:
- Journal of the American Veterinary Medical Association
- Year:
- 1988
- Authors:
- Hondalus, M K & Lofstedt, J
- Affiliation:
- Department of Large Animal Medicine · United States
Plain-English summary
A 16-year-old pony was experiencing occasional belly pain and was given too much phenylbutazone, a pain medication. This led to sores in the pony's esophagus, stomach, and the beginning of the small intestine, and the pony also developed diarrhea. Tests showed that the pony had a blood infection caused by Salmonella typhimurium, which was found in both its blood and stool. The treatment included giving fluids and medications to help with the infection and to protect the stomach, and thankfully, both the diarrhea and the sores healed. Overall, the treatment was successful.
Abstract
A 16-year-old pony with signs of intermittent abdominal pain was treated with phenylbutazone in excess of the recommended dosage. Endoscopy revealed ulceration of the esophagus, stomach, and proximal portion of small intestine. The pony developed diarrhea. Salmonella typhimurium was isolated from the blood and feces. Treatment included fluids, trimethoprim-sulfadiazine, sucralfate, and ranitidine hydrochloride. The diarrhea resolved, as did the gastrointestinal ulceration. This case was unusual because septicemia with salmonellosis is an uncommon finding in adult equids. Also, complications commonly seen in neonatal septicemia (septic arthritis, nephritis, and hepatitis) were not observed. Phenylbutazone toxicosis and stress were considered possible causes for the gastrointestinal ulceration.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/3372303/