Peer-reviewed veterinary case report
Sequence determination of a new parrot bornavirus-5 strain in Japan: implications of clade-specific sequence diversity in the regions interacting with host factors.
- Journal:
- Microbiology and immunology
- Year:
- 2016
- Authors:
- Komorizono, Ryo et al.
- Affiliation:
- Department of Viral Oncology
- Species:
- bird
Abstract
In this study, the genome sequence of a new parrot bornavirus-5 (PaBV-5) detected in Eclectus roratus was determined. Phylogenetic analysis showed that the genus Bornavirus is divided into three major clades and that PaBV-5 belongs to clade 2, which contains avian viruses that exhibit infectivity to mammalian cells. Sequence comparisons of the regions known to interact with host factors indicated that the clade 2 avian viruses possess sequences intermediate between the clade 1 mammalian viruses and the clade 3 avian viruses, suggesting that the identified regions might contribute to the differences in virological properties between the three clades.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/27166599/