Peer-reviewed veterinary case report
CT scan changes in lung leptospirosis in 10 dogs over 7 days
By Gendron, K et al.·Published in The Veterinary record·2014·VetSuisse Faculty·View original on PubMed →
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Original publication title: Serial CT features of pulmonary leptospirosis in 10 dogs.
- Species:
- dog
Plain-English summary
A group of 10 dogs with leptospirosis (a bacterial infection) showed serious breathing problems due to pulmonary hemorrhage syndrome. They underwent three CT scans over a week to monitor their lung condition. While one dog sadly died from respiratory failure shortly after the first scan, the others showed improvement over time, with many lung lesions reducing in severity. Most dogs had temporary lung changes that resolved by the end of the week. The study found that while the severity of lung issues varied, it did not directly affect whether the dogs survived their hospital stay.
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Abstract
Leptospirosis pulmonary haemorrhage syndrome (LPHS) is a frequent manifestation of Leptospira infection in dogs and is associated with a high morbidity and mortality. Three helical 16-slice thoracic CT scans were performed in 10 dogs naturally infected with Leptospira, within 24 hours of admission, and three and seven days later. Patients were sedated and scanned without breathhold, with a protocol adapted for rapid scanning. One dog died of respiratory failure on the morning following the first scan. On the initial scan, imaging features of LPHS included ground-glass nodules (10/10), peribronchovascular interstitial thickening (10/10), diffuse or patchy ground-glass opacity (9/10), solid nodules (8/10) and consolidation (7/10). Temporary bronchiolar dilation was observed in all dogs in association with peribronchovascular interstitial thickening, which had completely resolved at day 7. Nodules were with few exceptions assigned to the centrilobular region. Regression of lesion severity was observed after each subsequent scan. Consolidation and solid nodules changed over time into lesions of ground-glass attenuation. Pleural effusion (3/10) and mediastinal effusion (2/10) were mild and transient. Lesion severity appeared unassociated with survival to discharge.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24420873/