Peer-reviewed veterinary case report
How common is dust mite allergy in dogs with skin allergies in São
By Frezza, Ana Paula Di Martino et al.·Published in Research in veterinary science·2023·Department of Veterinary Clinic, Brazil·View original on PubMed →
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Original publication title: Seroprevalence of Dermatophagoides farinae-specific IgE in dogs with atopic dermatitis in São Paulo, Brazil.
- Species:
- dog
Plain-English summary
A group of 85 dogs with atopic dermatitis (a skin condition causing itching and inflammation) in São Paulo, Brazil, were tested for allergies to house dust mites. The results showed that an overwhelming majority of the dogs had high levels of specific antibodies (IgE) against common dust mite allergens, with 97.5% reacting to one particular allergen. This suggests that house dust mites are a significant cause of skin problems in these dogs. Understanding these allergens can help veterinarians choose more effective treatments for affected pets.
People also search for: dog itching treatment · atopic dermatitis in dogs · house dust mite allergy in dogs
Abstract
Canine atopic dermatitis (CAD) is a chronic, inflammatory, and pruritic disease of the skin resulting from the loss of the epidermal barrier, sensitization, and exacerbated production of IgE antibodies mainly directed against environmental allergens, especially to house dust mites. To select specific allergen immunotherapies with high efficacy, there are necessary studies with house dust mite allergens to improve both serological and intradermal tests. Therefore, the objective of this study was to evaluate the seroprevalence of IgE against Der f 2, Zen 1, and crude Dermatophagoides farinae allergens in dogs with AD in the State of São Paulo, Brazil. The sera of 85 dogs with clinically confirmed atopic dermatitis from the State of São Paulo (Brazil) was collected. In addition, an indirect ELISA test was conducted to detect allergen-specific serum IgE. IgE seropositivity was observed in 97.5% of the dogs for Der f 2, 95.0% for Zen 1, and 92.5% for the crude mite allergens. Due to this high prevalence of IgE specific to these allergens, we suggest that Der f 2 and Zen 1 can be considered major allergens for dogs in the State of São Paulo.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/37713746/