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Peer-reviewed veterinary case report

Rabies and distemper immunity in Korean military working dogs tested

By Kim, Ha-Hyun et al.·Published in The Journal of veterinary medical science·2018·Viral Disease Research Division, South Korea·View original on PubMed

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Original publication title: Serosurvey of rabies virus, canine distemper virus, parvovirus, and influenza virus in military working dogs in Korea.

Species:
dog

Plain-English summary

A group of military working dogs in Korea were tested for immunity against rabies, canine distemper, and parvovirus after vaccination. The results showed that nearly all the dogs had strong immunity to rabies (97.4%), canine distemper (94.8%), and parvovirus (100%). However, two 1-year-old dogs in areas with rabies outbreaks had lower immunity levels. None of the dogs showed signs of exposure to canine influenza. This information is crucial for ensuring these working dogs remain protected against these serious diseases.

People also search for: dog rabies vaccination effectiveness · canine distemper symptoms · parvovirus immunity in dogs

Abstract

Rabies virus (RABV), canine distemper virus (CDV), canine parvovirus type-2 (CPV-2), and canine influenza A virus (CIV) are important contagious pathogens in canine populations. To assess post-vaccination immunity against RABV, CDV and CPV-2, and serological evidence of exposure to influenza A virus in military working dogs (MWDs) in Korea, we tested blood samples of 78 MWDs by fluorescent antibody virus neutralization (FAVN) for RABV, and by commercially available enzyme-linked immunosorbent assay (ELISA) for CDV, CPV-2, and CIV. Korean MWDs had high antibody-positive rates against RABV (97.4%, ≥0.5 IU/ml), CDV (94.8%), and CPV (100%). All dogs tested seronegative (0/78; 0%) for influenza A virus. Two 1-year-old dogs stationed in known rabies outbreak areas (Gangwon and Gyeonggi) exhibited VNA titers below the protective level (0.06 and 0.29 IU/ml, respectively). The breed and sex of MWDs were not significantly associated with antibody titers for RABV, CDV, or CPV; however, age was significantly associated with CPV antibody titers, while region of residence was associated with CDV antibody titer. Taken together, the data presented here provide important insights necessary for post-vaccination management and control of infectious diseases in MWDs.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30068896/