Peer-reviewed veterinary case report
Antibodies to Malassezia yeast in dogs with atopic dermatitis
By Nuttall, T J & Halliwell, R E·Published in Veterinary dermatology·2001·University of Edinburgh Hospital for Small Animals, United Kingdom·View original on PubMed →
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Original publication title: Serum antibodies to Malassezia yeasts in canine atopic dermatitis.
- Species:
- dog
Plain-English summary
A group of dogs with atopic dermatitis (a skin allergy) were tested for antibodies against Malassezia yeasts, which can cause skin infections. The study found that dogs with atopic dermatitis had higher levels of certain antibodies compared to healthy dogs and those without allergies, indicating a possible link between the allergy and Malassezia infections. However, there was no difference in antibody levels between atopic dogs showing skin or ear infections and those that did not. Understanding these antibody levels may help veterinarians better manage skin issues in allergic dogs.
People also search for: dog skin allergy treatment · Malassezia dermatitis in dogs · why is my dog itching · dog ear infection symptoms · atopic dermatitis in dogs
Abstract
Significant numbers of humans with atopic dermatitis develop Malassezia-specific IgE. Immediate skin-test reactivity to Malassezia has been demonstrated in atopic dogs. The aim of this study was to compare the serum IgG and IgE response to Malassezia in atopic dogs with and without clinical evidence of Malassezia dermatitis and/or otitis, nonatopic dogs with clinical evidence of Malassezia dermatitis and/or otitis and healthy dogs. Cytology was used to diagnose clinically significant Malassezia dermatitis and otitis. Contact plate cultures confirmed the validity of this technique. Reproducible enzyme-linked immunosorbent assays for Malassezia-specific IgG and IgE in canine serum were established. Atopic dogs had significantly higher serum IgG and IgE levels than either healthy dogs or nonatopic dogs with clinical evidence of Malassezia dermatitis and/or otitis. There was no significant difference in IgG and IgE levels between atopic dogs with and without clinical evidence of Malassezia dermatitis and/or otitis. The implications of these findings in the pathogenesis and management of canine atopic dermatitis are discussed.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/11844222/