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Peer-reviewed veterinary case report

Antibodies to Malassezia yeast in dogs with atopic dermatitis

By Nuttall, Timothy J. & Halliwell, Richard E. W.·Published in Veterinary Dermatology·2001·View original on Crossref

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Original publication title: Serum antibodies toMalasseziayeasts in canine atopic dermatitis

Species:
dog

Plain-English summary

A group of dogs with atopic dermatitis (a skin allergy) were tested for antibodies against Malassezia, a type of yeast that can cause skin and ear infections. The study found that atopic dogs had higher levels of specific antibodies compared to healthy dogs and non-allergic dogs with skin issues. This suggests that atopic dogs may be more prone to Malassezia infections, even if they don’t show visible symptoms. Understanding these antibody levels can help veterinarians better manage skin allergies in dogs.

People also search for: dog skin allergy treatment · Malassezia dermatitis in dogs · atopic dermatitis symptoms in dogs

Abstract

AbstractSignificant numbers of humans with atopic dermatitis developMalassezia‐specific IgE. Immediate skin‐test reactivity toMalasseziahas been demonstrated in atopic dogs. The aim of this study was to compare the serum IgG and IgE response toMalasseziain atopic dogs with and without clinical evidence ofMalasseziadermatitis and/or otitis, nonatopic dogs with clinical evidence ofMalasseziadermatitis and/or otitis and healthy dogs. Cytology was used to diagnose clinically significantMalasseziadermatitis and otitis. Contact plate cultures confirmed the validity of this technique. Reproducible enzyme‐linked immunosorbant assays forMalassezia‐specific IgG and IgE in canine serum were established. Atopic dogs had significantly higher serum IgG and IgE levels than either healthy dogs or nonatopic dogs with clinical evidence ofMalasseziadermatitis and/or otitis. There was no significant difference in IgG and IgE levels between atopic dogs with and without clinical evidence ofMalasseziadermatitis and/or otitis. The implications of these findings in the pathogenesis and management of canine atopic dermatitis are discussed.

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Original publication on Crossref: https://doi.org/10.1046/j.0959-4493.2001.00261.x