Peer-reviewed veterinary case report
Blood protein changes in dogs with natural babesiosis infection
By Ulutas, Bulent et al.·Published in Veterinary clinical pathology·2005·Faculty of Veterinary Medicine·View original on PubMed →
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Original publication title: Serum concentration of some acute phase proteins in naturally occurring canine babesiosis: a preliminary study.
- Species:
- dog
Plain-English summary
A group of dogs with babesiosis, a disease caused by a blood parasite, showed changes in certain proteins in their blood that can help diagnose and monitor the illness. Specifically, levels of C-reactive protein and ceruloplasmin were higher in these dogs, while haptoglobin levels were lower compared to healthy dogs. This suggests that measuring these proteins could be useful for veterinarians in assessing the severity of babesiosis in dogs.
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Abstract
BACKGROUND: Serum concentrations of acute phase proteins can provide valuable diagnostic information in the detection, prognosis, or monitoring of disease. Information available on the acute phase response in naturally occurring canine babesiosis is limited. OBJECTIVE: The purpose of this investigation was to retrospectively evaluate serum concentrations of haptoglobin, C-reactive protein, and ceruloplasmin in dogs naturally infected with Babesia canis. METHODS: Haptoglobin, C-reactive protein, and ceruloplasmin concentrations were measured in serum samples from dogs with uncomplicated (n = 6) and complicated (n = 1) babesiosis and compared with 6 healthy dogs. RESULTS: Serum C-reactive protein and ceruloplasmin concentrations were significantly higher in dogs with babesiosis; however, serum haptoglobin concentration was significantly lower compared with control dogs (P <.01). CONCLUSIONS: Results of this study suggest that acute phase protein concentrations could be beneficial in the diagnosis and determination of the severity of babesiosis in dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15902667/