Peer-reviewed veterinary case report
High blood gastrin linked to stomach damage in dogs with chronic gut
By García-Sancho, Mercedes et al.·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2005·Department of Animal Medicine and Surgery, Spain·View original on PubMed →
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Original publication title: Serum gastrin in canine chronic lymphocytic-plasmacytic enteritis.
- Species:
- dog
Plain-English summary
A group of 15 dogs with chronic lymphocytic-plasmacytic enteritis (a type of intestinal inflammation) had higher levels of a hormone called gastrin compared to 5 healthy dogs. This increase in gastrin was linked to more severe stomach lesions in the affected dogs. The findings suggest that gastrin might contribute to ongoing stomach inflammation in dogs with this intestinal condition. If your dog has gastrointestinal issues, discussing gastrin levels and potential treatments with your veterinarian could be beneficial.
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Abstract
This study evaluates serum gastrin concentrations in dogs with chronic lymphocytic-plasmacytic enteritis, as well as its possible relationship with the severity of lesions present in the stomach. To achieve this aim, 5 dogs without gastrointestinal disease and 15 dogs with chronic lymphocytic-plasmacytic enteritis were included. Serum gastrin concentrations were significantly increased in dogs with chronic lymphocytic-plasmacytic enteritis compared with those in dogs without gastrointestinal disease. Also, there was a positive correlation between the severity of the gastric lesion and the serum gastrin concentration. Our findings indicate the possibility that gastrin plays a role in the etiology of an accompanying chronic antral gastritis in canine chronic lymphocytic-plasmacytic enteritis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16152719/