Peer-reviewed veterinary case report
Changes in blood IL-6 and IL-10 in female dogs with pyometra
By Dąbrowski, Roman et al.·Published in Acta veterinaria Scandinavica·2015·Department and Clinic of Animal Reproduction·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Serum IL-6 and IL-10 concentrations in bitches with pyometra undergoing ovariohysterectomy.
- Species:
- dog
Plain-English summary
A female dog with a serious uterine infection called pyometra was treated with surgery to remove her uterus and ovaries. Before the surgery, her blood tests showed high levels of certain proteins (IL-6 and IL-10) that indicate inflammation. After the surgery, these protein levels dropped significantly, suggesting that the surgery was effective in treating the infection. Monitoring these proteins can help veterinarians assess recovery after surgery.
People also search for: dog pyometra symptoms · female dog surgery recovery · IL-6 IL-10 levels in dogs
Abstract
BACKGROUND: Pyometra is a serious bacterial infection of the uterus affecting female dogs and manifests as an accumulation of pus in the uterine lumen. The aim of the study was to assess changes in serum interleukin (IL)-6 and IL-10 concentrations in bitches with pyometra undergoing ovariohysterectomy. FINDINGS: Blood samples were collected from healthy bitches (controls) and bitches with pyometra before surgery, and 3 and 10 days after ovariohysterectomy. Before surgery, bitches with pyometra had significantly higher serum concentrations of IL-6 and IL-10 than the controls. After surgery, the serum concentration of IL-6 and IL-10 decreased significantly. In healthy dogs, the concentration of IL-6 and IL-10 showed a significant increase 3 days after surgery followed by a decrease on day 10. CONCLUSION: An increase in serum concentrations of IL-6 and IL-10 was present before surgery in bitches with pyometra and 3 days after ovariohysterectomy in healthy controls. Concentrations decreased after ovariohysterectomy and/or proper healing, suggesting that these cytokines can be useful for assessment of the postoperative period in bitches.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/26410584/