Peer-reviewed veterinary case report
High liver enzymes linked to high triglycerides in Miniature
By Xenoulis, Panagiotis G et al.·Published in Journal of the American Veterinary Medical Association·2008·Department of Small Animal Clinical Sciences, United States·View original on PubMed →
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Original publication title: Serum liver enzyme activities in healthy Miniature Schnauzers with and without hypertriglyceridemia.
- Species:
- dog
Plain-English summary
A study looked at Miniature Schnauzers to see if high fat levels in the blood (hypertriglyceridemia) were linked to liver problems. They found that dogs with moderate to severe high fat levels had significantly higher liver enzyme levels compared to those with normal fat levels. This suggests that if your Miniature Schnauzer has high triglycerides, it might also have liver issues. Regular check-ups and blood tests can help monitor liver health, especially if your dog has high fat levels in its blood.
People also search for: Miniature Schnauzer liver enzyme levels · high triglycerides in dogs · dog liver health checkup
Abstract
OBJECTIVE: To determine whether hypertriglyceridemia in healthy Miniature Schnauzers is associated with high serum liver enzyme activities. DESIGN: Cross-sectional study. ANIMALS: 65 Miniature Schnauzers with serum triglyceride concentrations within the reference range (group 1), 20 Miniature Schnauzers with slightly high serum triglyceride concentrations (group 2), and 20 Miniature Schnauzers with moderately to severely high serum triglyceride concentrations (group 3). PROCEDURES: Questionnaires regarding each dog's medical history were completed, and serum alkaline phosphatase (ALP), alanine aminotransferase (ALT), aspartate aminotransferase (AST), and G-glutamyltransferase (GGT) activities were measured. RESULTS: Median serum ALP activity was significantly higher in group 3 than in group 1 or 2 dogs, but was not significantly higher in group 2 than in group 1 dogs. Median serum ALT activity was significantly higher in group 3 than in group 1 dogs, but was not significantly different between any of the other groups. Compared with group 1 dogs, group 2 and 3 dogs were significantly more likely to have high serum ALP activity (odds ratio, 26.2 and 192.6, respectively). Group 3 dogs also were significantly more likely to have high serum ALT activity (odds ratio, 8.0), serum AST activity (odds ratio, 3.7), and serum GGT activity (odds ratio, 11.3), compared with group 1 dogs. Group 3 dogs were significantly more likely (odds ratio, 31.0) to have > or = 2 high serum liver enzyme activities than were group 1 dogs. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggested that moderate to severe hypertriglyceridemia was associated with high serum liver enzyme activities in Miniature Schnauzers.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18167110/