Peer-reviewed veterinary case report
Triglyceride and cholesterol levels in dogs with pancreatitis
By Xenoulis, Panagiotis G et al.·Published in Journal of veterinary internal medicine·2020·Department of Small Animal Clinical Sciences, United States·View original on PubMed →
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Original publication title: Serum triglyceride and cholesterol concentrations and lipoprotein profiles in dogs with naturally occurring pancreatitis and healthy control dogs.
- Species:
- dog
Plain-English summary
A group of 17 dogs diagnosed with pancreatitis had their blood tested for fat levels compared to 53 healthy dogs. While most dogs with pancreatitis had normal fat levels, a few showed higher triglycerides and cholesterol. The dogs with pancreatitis had different fat profiles in their blood compared to healthy dogs, indicating changes in how their bodies process fats. This information can help veterinarians understand and manage pancreatitis better in dogs.
People also search for: dog pancreatitis symptoms · high triglycerides in dogs · dog cholesterol treatment
Abstract
BACKGROUND: Previous studies have reported an association between hyperlipidemia and pancreatitis in dogs, but details of this association remain poorly defined. HYPOTHESIS/OBJECTIVES: To compare serum triglyceride and cholesterol concentrations and lipoprotein profiles between dogs with naturally occurring pancreatitis and healthy dogs. ANIMALS: Seventeen dogs with a clinical diagnosis of pancreatitis (Group 1) and 53 healthy control dogs (Group 2). METHODS: Prospective case-control study. RESULTS: In Group 1, 3/17 dogs (18%) had hypertriglyceridemia whereas in Group 2, 4/53 dogs (7.5%) had hypertriglyceridemia (odds ratio [OR], 2.63; 95% confidence interval [CI], 0.52-13.14; P = .35). A significant difference was found in serum triglyceride concentrations between Group 1 (median, 67 mg/dL) and Group 2 (median, 54 mg/dL; P = .002). In Group 1, 4/17 dogs (24%) had hypercholesterolemia, whereas 1/53 (1.9%) dogs in Group 2 had hypercholesterolemia (OR, 16; 95% CI, 1.64-155.5; P = .01). No significant difference was found in serum cholesterol concentrations between Group 1 (median, 209 mg/dL) and Group 2 (median, 227 mg/dL; P = .56). Lipoprotein profiles were significantly different between Group 1 and Group 2 dogs (Eigenvalues, 0.6719; R= 1.0; P = .001). CONCLUSIONS AND CLINICAL IMPORTANCE: Most dogs with pancreatitis (>70%) had serum triglyceride and cholesterol concentrations within reference intervals. In the small percentage of dogs that had hypertriglyceridemia, hypercholesterolemia, or both, increases were mild. Important differences were identified in lipoprotein profiles between dogs with pancreatitis and healthy control dogs. Dogs with pancreatitis had higher low-density lipoprotein fractions and lower triglyceride-rich lipoprotein and high-density lipoprotein fractions than healthy dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32012351/