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Peer-reviewed veterinary case report

Cat with congenital hypothyroidism developed severe artery

By Yusuke Tanaka et al.·Published in Journal of Veterinary Medical Science·2020·View original on Semantic Scholar

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Original publication title: Severe calcification of systemic blood vessel walls caused by continuous hypercalcemia in a cat with congenital hypothyroidism

Species:
cat

Plain-English summary

A 4-year-old male Japanese domestic cat was diagnosed with congenital hypothyroidism, which led to high calcium levels in his blood. Despite receiving fluid therapy, the cat unfortunately passed away. An examination revealed enlarged parathyroid glands and thickened blood vessel walls, indicating severe calcification. This case highlights a rare connection between hypothyroidism and secondary hyperparathyroidism, which can lead to serious health issues in cats.

People also search for: cat congenital hypothyroidism symptoms · cat high calcium treatment · cat kidney disease and parathyroid issues

Abstract

A 97-day-old male Japanese domestic cat was diagnosed as congenital hypothyroidism. During the treatment, continuous hypercalcemia was detected. Although fluid therapy was performed, the cat died at the age of 1785 days. At autopsy, both parathyroid glands were enlarged, and elastic arterial walls were increased in thickness and hardness. Histopathological examination revealed hyperplasia of both parathyroid glands and interstitial fibrosis of bilateral kidneys. Severe calcification of the tunica media and tunica externa in systemic elastic and muscular arteries were also observed. These calcifications were considered to be due to renal secondary hyperparathyroidism. In the present case, hypothyroidism might have caused hyperparathyroidism through renal failure. In veterinary medicine, this is the first reported case of hypothyroidism accompanied with hyperparathyroidism.

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Original publication on Semantic Scholar: https://www.semanticscholar.org/paper/32879233