Peer-reviewed veterinary case report
Dog with severe acid buildup after acetazolamide overdose recovers
By Johnston, L et al.·Published in Australian veterinary journal·2021·Internal Medicine, Australia·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Severe metabolic acidosis due to acetazolamide intoxication in a dog.
- Species:
- dog
Plain-English summary
A 1-year-old neutered male Siberian Husky was brought to the vet after accidentally eating a large amount of acetazolamide, a medication that can affect how the body balances acids and bases. The dog showed signs of severe breathing problems due to a condition called metabolic acidosis, which also caused low potassium levels. The vet treated him with intravenous and later oral sodium bicarbonate and potassium supplements. Thankfully, the dog made a full recovery within nine days.
People also search for: dog breathing problems after eating medication · Siberian Husky acetazolamide overdose · dog metabolic acidosis treatment
Abstract
CASE REPORT: This case report describes the clinical signs and case management of a 1-year-old neutered male Siberian Husky that accidentally ingested 635 mg/kg of oral acetazolamide (a carbonic anhydrase inhibitor). The dog presented with severe tachypnoea due to the development of hyperchloraemic metabolic acidosis and associated hypokalaemia that persisted for 7 days. Clinical and biochemical changes resolved with intravenous and subsequent oral supplementation of sodium bicarbonate and potassium. Complete recovery occurred within 9 days of presentation. CONCLUSION: To the authors' knowledge, this is the first case that reports overdosage of an oral carbonic anhydrase inhibitor in a dog and subsequent recovery with adequate supplementation and supportive care.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33025586/