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Peer-reviewed veterinary case report

Severity-dependent atrial remodeling and atrial fibrillation vulnerability in a clinically relevant aortic regurgitation mouse model.

Journal:
JCI insight
Year:
2026
Authors:
Lakin, Robert et al.
Affiliation:
Department of Biology · Canada

Abstract

Severity of aortic regurgitation correlates with atrial stretch and fibrillation. Uncovering stretch-mediated atrial remodeling prior to ventricular pathology will help define optimal timing of interventions.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/41860435/