Peer-reviewed veterinary case report
SGLT2 inhibitors for treating diabetes in cats
By Audrey K. Cook & Ellen N. Behrend·Published in Journal of Veterinary Pharmacology and Therapeutics·2024·View original on Semantic Scholar →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: SGLT2 inhibitor use in the management of feline diabetes mellitus
- Species:
- cat
Plain-English summary
A cat with diabetes may benefit from new oral medications called SGLT2 inhibitors, specifically bexagliflozin and velagliflozin, which have recently been approved for use in cats. These medications help lower blood sugar levels and improve symptoms quickly, making them a good option for many newly diagnosed cats. However, it's important that the cat still has some ability to produce insulin to avoid complications like diabetic ketoacidosis. Pet owners should work closely with their veterinarian to monitor their cat's condition and ensure the best treatment approach.
People also search for: cat diabetes treatment · SGLT2 inhibitors for cats · feline diabetes symptoms · managing cat blood sugar levels
Abstract
Abstract Sodium‐glucose cotransporter‐2 (SGLT2) inhibitors are routinely used in the management of human type 2 diabetes and have been shown to effectively mitigate hyperglycemia and reduce the risks of cardiovascular and renal compromise. Two SGLT2 inhibitors, namely bexagliflozin and velagliflozin, were recently FDA approved for the treatment of uncomplicated feline diabetes mellitus. These oral hypoglycemic agents are a suitable option for many newly diagnosed cats, with rapid improvements in glycemic control and clinical signs. Suitable candidates must have some residual β‐cell function, as some endogenous insulin production is required to prevent ketosis. Appropriate patient selection and monitoring are necessary, and practitioners should be aware of serious complications such as euglycemic diabetic ketoacidosis.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on Semantic Scholar: https://www.semanticscholar.org/paper/38954371