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Peer-reviewed veterinary case report

Shedding of Escherichia coli O157:H7 in calves is reduced by prior colonization with the homologous strain.

Journal:
Applied and environmental microbiology
Year:
2007
Authors:
Naylor, Stuart W et al.
Affiliation:
Scottish Agricultural College · United Kingdom

Abstract

Enterohemorrhagic Escherichia coli O157:H7 has a natural reservoir in the intestinal tracts of cattle. Colonization is asymptomatic and transient, but it is not clear if protective immunity is induced. This study demonstrates that prior colonization induces humoral immune responses to bacterial antigens and reduces bacterial shedding after experimental challenge with the homologous strain.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/17449700/