Peer-reviewed veterinary case report
Short-term results of mitral valve replacement with pig valves in dogs
By Takashima, Kazuaki et al.·Published in The Journal of veterinary medical science·2007·Animal Clinical Research Foundation, Japan·View original on PubMed →
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Original publication title: Short-term performance of mitral valve replacement with porcine bioprosthetic valves in dogs.
- Species:
- dog
Plain-English summary
Five beagle dogs underwent surgery to replace their mitral valves with new porcine bioprosthetic valves. The surgery went smoothly, and the dogs showed no signs of complications like blood clots or valve leakage one week later. Although there was a significant change in heart pressure measurements after the surgery, it remained within a normal range. Overall, the replacement valves appeared to work well in the short term, suggesting this could be a promising treatment option for dogs with mitral valve issues.
People also search for: dog mitral valve replacement · beagle heart surgery · porcine valve for dogs · dog heart valve surgery recovery
Abstract
Porcine bioprosthetic valves cross-linked with glutaraldehyde and polyepoxy compound were newly developed for mitral valve replacement (MVR) in dogs. Five beagle dogs were performed a left thoracotomy and underwent MVR using the porcine bioprosthetic valves during cardiopulmonary bypass (CPB). A vein catheter inserted into right atrium and a vent catheter inserted into the right ventricle to drain. The hemodynamic conditions of CPB were excellent during surgery. The left atrial pressure was measured before and after MVR; there was no significant difference and it was normal. Thrombosis and the prosthetic valve regurgitation were not observed one week after MVR. Pressure half time (PHT) prolonged significantly (P<0.05) from 31.40 +/- 4.0 msec presurgery to 99.20 +/- 19.4 msec at seven days after MVR, although it indicated the normal range as the bioprosthetic valve. The symptom of the prosthetic valve failure was not observed. This study indicated that the MVR using porcine bioprosthetic valves under CPB might have been effective in dogs as a short-term evaluation.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17827884/