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Peer-reviewed veterinary case report

Silent spread of H5N1 in vaccinated poultry.

Journal:
Nature
Year:
2006
Authors:
Savill, Nicholas J et al.
Affiliation:
University of Edinburgh · United Kingdom
Species:
bird

Abstract

International debate on the merits of vaccinating poultry against the H5N1 influenza A virus has raised concerns about the possibility of an increased risk of between-flock transmission before outbreaks are detected. Here we show that this 'silent spread' can occur because of incomplete protection at the flock level, even if a vaccine is effective in individual birds. The use of unvaccinated sentinels can mitigate, although not completely eliminate, the problem.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/16915278/