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Peer-reviewed veterinary case report

Puppy with pneumonia had three infections including distemper

By Chvala, S et al.·Published in Veterinary pathology·2007·Department of Pathobiology·View original on PubMed

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Original publication title: Simultaneous canine distemper virus, canine adenovirus type 2, and Mycoplasma cynos infection in a dog with pneumonia.

Species:
dog

Plain-English summary

A 5-month-old female Miniature Pinscher was brought in with severe breathing problems, making croaking sounds, and losing weight. Unfortunately, the puppy was diagnosed with a serious triple infection involving canine distemper virus, canine adenovirus type 2, and Mycoplasma cynos, which led to pneumonia. Despite efforts to treat her, the condition was too severe, and she was euthanized to prevent further suffering. This case highlights the dangers of multiple infections in young dogs and the importance of prompt veterinary care.

People also search for: dog breathing problems · Miniature Pinscher pneumonia treatment · canine distemper virus symptoms

Abstract

The present case is the first description of a triple infection with canine distemper virus (CDV), canine adenovirus (CAV) type 2, and Mycoplasma cynos in a dog. The 5-month-old female Miniature Pinscher was euthanized because of dyspnea, croaking lung sounds, weight loss, and lymphopenia. Pathologic examination revealed a fibrinous necrotizing pneumonia with large amphophilic intranuclear and acidophilic intracytoplasmatic inclusion bodies in different lung cells. Immunohistochemically, CDV antigen was present in lung and many other organs. In situ hybridization for detection of CAV nucleic acid showed positive signals in the lung only. Polymerase chain reaction of lung tissue and consecutive sequencing of the amplification product identified CAV type 2. Bacteriologic examination of lung tissue yielded large amounts of M cynos. This infection was confirmed by immunohistochemistry detecting abundant positive signals in the lung tissue.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17606512/