Peer-reviewed veterinary case report
Single high-dose radiation treatment for dog rectal cancer
By TURREL, JANE M. & THEON, ALAIN P.·Published in Veterinary Radiology·1986·View original on Crossref →
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Original publication title: SINGLE HIGH‐DOSE IRRADIATION FOR SELECTED CANINE RECTAL CARCINOMAS
- Species:
- dog
Plain-English summary
A 7-year-old mixed-breed dog was treated for rectal cancer with a single high dose of radiation therapy. This treatment was given to tumors located in the lower part of the rectum and anal canal, and it successfully shrank six out of seven tumors without causing significant side effects. Most dogs experienced minimal reactions to the radiation, and while the average time without cancer was about 9.7 months, many dogs lived for over a year after treatment. This approach shows promise for treating specific cases of rectal cancer in dogs.
People also search for: dog rectal cancer treatment · radiation therapy for dogs · dog anal canal tumor survival rate
Abstract
Single high‐dose radiotherapy was evaluated as a treatment for seven adenocarcinomas of the distal half of the rectum and anal canal in six dogs. A single dose of radiation ranging from 15–25 Gy was given to the tumor by the use of a well‐collimated, low‐energy orthovoltage x‐ray beam. Six tumors had complete response to treatment. Minimal acute radiation reaction was observed in all dogs. The tumor control and survival rates at 1 year were estimated to be 46% and 67%, respectively. Median and mean tumor‐free times were 6.0 and 9.7 months, respectively; and median and mean survival times were 7.0 and 11.3 months, respectively. No long‐term side effects were noted. Proper patient selection was critical because of the physical limitations of the procedure. Tumors should be less than 3 cm in diameter, confined to the rectal wall, and be located in the distal half of the rectum and anal canal. This preliminary study documented the fasibility, efficacy, and lack of toxicity of single high‐dose radiotherapy for selected rectal carcinomas.
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Search related cases →Original publication on Crossref: https://doi.org/10.1111/j.1740-8261.1986.tb00021.x