Peer-reviewed veterinary case report
Is a single oral dose of D-allulose safe for dogs?
By Nishii, Naohito et al.·Published in The Journal of veterinary medical science·2016·Joint Department of Veterinary Medicine, Japan·View original on PubMed →
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Original publication title: Single oral dose safety of D-allulose in dogs.
- Species:
- dog
Plain-English summary
A group of healthy dogs was given a single oral dose of D-allulose, a type of sugar, to see if it was safe. One dog vomited, and five others had temporary diarrhea after receiving the higher dose, but all dogs remained active and had a good appetite during the study. Blood tests showed a slight drop in blood sugar levels without affecting insulin levels, and there was a mild increase in a liver enzyme after 12 to 48 hours. Overall, the study suggests that D-allulose does not cause serious toxicity in dogs.
People also search for: dog vomiting after sugar · D-allulose safety for dogs · dog diarrhea after new food
Abstract
Healthy dogs were administered acute oral doses of D-allulose (also called D-psicose) to evaluate its toxicity. Six dogs received oral doses of either a placebo or D-allulose solution (1 and 4 g/kg) on three different study days. One dog experienced vomiting, and five dogs showed transient diarrhea when 4 g/kg of D-allulose was administered. All dogs were active and had a good appetite throughout the study period. Blood glucose concentration slightly decreased without a rise in plasma insulin concentration 2 hr after D-allulose administration. Plasma alkaline phosphatase activities showed a mild increase between 12 and 48 hr after D-allulose administration. These data suggested that a single oral dose of D-allulose does not show severe toxicity in dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/26972334/