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Peer-reviewed veterinary case report

Two young female Beagles with artery hardening in heart node

By Hamlen, H J et al.·Published in Journal of the American Veterinary Medical Association·1994·Department of Comparative Medicine·View original on PubMed

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Original publication title: Sinoatrial node arteriosclerosis in two young dogs.

Species:
dog

Plain-English summary

Two 11-month-old female Beagles were brought to the vet with signs of heart problems. Tests showed that the arteries supplying the heart's natural pacemaker (sinoatrial node) were thickened and narrowed, which can affect how the heart beats. The exact cause of this condition is unclear, but it could be linked to other serious issues like blood vessel inflammation or hardening of the arteries. Unfortunately, the prognosis for these young dogs is uncertain, and further treatment options would need to be discussed with a veterinarian.

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Abstract

Two 11-month-old 7-kg unrelated female Beagles had clinical signs referable to the cardiovascular system. Histologic studies in both dogs revealed strikingly similar findings of sclerosis of the arteries of the sinoatrial node. Histologic changes included intimal thickening and fibrosis, with marked luminal narrowing; medial hypertrophy, fibrosis, and smooth muscle cell proliferation; and elastic fiber disruption and reduplication. Possible differential diagnoses for this condition included systemic necrotizing vasculitis (canine pain syndrome), coronary polyarteritis, and atherosclerosis.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/8175470/