Peer-reviewed veterinary case report
Sinonasal and sino-orbital fungal infection in 23 cats and treatment
By Barrs, V R et al.·Published in Veterinary journal (London, England : 1997)·2012·Faculty of Veterinary Science, United Kingdom·View original on PubMed →
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Original publication title: Sinonasal and sino-orbital aspergillosis in 23 cats: aetiology, clinicopathological features and treatment outcomes.
- Species:
- cat
Plain-English summary
A group of 23 cats, aged 1.5 to 13 years, were diagnosed with fungal infections in their sinuses or around their eyes, known as sinonasal or sino-orbital aspergillosis. The most common fungus found was Neosartorya spp., with some cases involving Aspergillus fumigatus. Cats with sinonasal infections tended to have a better chance of recovery compared to those with sino-orbital infections. Treatment details weren't specified, but identifying the specific fungus helped guide the care.
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Abstract
Aetiology, clinicopathological findings and treatment outcomes were documented in 23 cats (1.5-13 years of age) with sinonasal (SNA, n=6) or sino-orbital (SOA, n=17) aspergillosis. Cases recruited retrospectively and prospectively were included if fungal hyphae were identified on cytological or histological examination and the fungal pathogen was identified by PCR and DNA sequencing (ITS1 or ITS1-5.8S-ITS2 regions, rDNA gene cluster). Fungal culture was positive in 22/23 cases. In cases of SNA, the fungal pathogen was Aspergillus fumigatus (n=4), Neosartorya fischeri or A. lentulus (n=1) or a non-speciated Neosartorya spp. (n=1). In all cases of SOA (n=17), the fungal pathogen was identified as Neosartorya spp. Nine cats had brachycephalic conformation. Cats with SNA were more likely to be infected with A. fumigatus and had a better prognosis than cats with SOA.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21388842/