Peer-reviewed veterinary case report
Sinonasal angiofibroma in a horse.
- Journal:
- Journal of comparative pathology
- Year:
- 2025
- Authors:
- Schollmeyer, Magdalena et al.
- Affiliation:
- Institute of Veterinary Pathology · Germany
- Species:
- horse
Plain-English summary
A 34-year-old Haflinger gelding (a type of horse) had a large growth inside his nose that came back after it was partially removed. Unfortunately, the horse was euthanized, and further examination showed that the mass had started in the left maxillary sinus (a space near the nose) and had filled up the left side of the nasal cavity. Tests on the tissue revealed that the growth was a type of tumor called an angiofibroma, which is made up of blood vessels and certain types of cells. The treatment did not work as hoped, leading to the decision for euthanasia.
Abstract
A 34-year-old Haflinger gelding presented with a unilateral, expansile, intranasal mass that regrew after partial excision. After euthanasia, a large pedunculated mass that originated from the left caudal maxillary sinus and obliterated the left nasal cavity was seen by radiological and macroscopic examination. Histopathology revealed a poorly cellular, expansile, well-vascularized neoplasm composed of a loosely arranged meshwork of spindle cells and collagen fibres. Spindle cells were immunopositive for alpha-smooth muscle actin and occasionally for vimentin, whereas endothelial cells immunolabelled for factor VIII-related antigen. Based on clinical, radiological, macroscopic and microscopic similarities to canine and human cases, the mass was diagnosed as an angiofibroma.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/40367666/