Peer-reviewed veterinary case report
Sinonasal tumors in 3 dogs after sinus fungus treatment
By Greci, Valentina et al.·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2009·Department of Veterinary Clinical Sciences, Italy·View original on PubMed →
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Original publication title: Sinonasal tumor in 3 dogs after successful topical treatment for frontal sinus aspergillosis.
- Species:
- dog
Plain-English summary
Three dogs developed nasal tumors after being treated for a fungal infection called aspergillosis. They had received a topical medication called clotrimazole, which successfully cleared the infection, but several months later, they were diagnosed with sinonasal tumors. All three dogs also had chronic inflammation in their sinuses before the tumors were found. The study suggests that the inflammation from the original infection and treatment may have contributed to the tumor development.
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Abstract
Three dogs diagnosed with aspergillosis developed sinonasal tumors several months after successful treatment with topical clotrimazole solution. Chronic rhinosinusitis was also detected in all cases prior to diagnosis of sinonasal tumors. The inflammatory response to Aspergillus, clotrimazole treatment, and chronic inflammation after treatment are discussed as possible neoplastic promoting factors.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20119545/