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Peer-reviewed veterinary case report

Sinonasal tumor in 3 dogs after successful topical treatment for frontal sinus aspergillosis.

Journal:
The Canadian veterinary journal = La revue veterinaire canadienne
Year:
2009
Authors:
Greci, Valentina et al.
Affiliation:
Department of Veterinary Clinical Sciences · Italy
Species:
dog

Abstract

Three dogs diagnosed with aspergillosis developed sinonasal tumors several months after successful treatment with topical clotrimazole solution. Chronic rhinosinusitis was also detected in all cases prior to diagnosis of sinonasal tumors. The inflammatory response to Aspergillus, clotrimazole treatment, and chronic inflammation after treatment are discussed as possible neoplastic promoting factors.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/20119545/