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Peer-reviewed veterinary case report

Site-selective reactions of hydrazonoyl chlorides with cyanoacetic hydrazide and its N-arylidene derivatives and anti-aggressive activity of prepared products.

Journal:
Archives of pharmacal research
Year:
2013
Authors:
Shawali, Ahmad Sami et al.
Affiliation:
Department of Chemistry

Abstract

Reactions of hydrazonoyl halides with cyanoacetic hydrazide and its N-arylidene derivatives proceeded site-selectively and afforded the respective pyrazolo[3,4-d]pyridazine and aldehyde N-(1-aryl-3-acetyl-4-cyanopyrazol-5-yl)hydrazone derivatives. The structures of the products were elucidated on the basis of their spectral and elemental analyses. The anti-aggressive activity of the compounds prepared was screened.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/23483436/