Peer-reviewed veterinary case report
Bone tumors causing lameness in older Golden Retrievers
By Schultz, Ryan M et al.·Published in Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·2007·Davis Veterinary Medical Teaching Hospital, United States·View original on PubMed →
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Original publication title: Skeletal lesions of histiocytic sarcoma in nineteen dogs.
- Species:
- dog
Plain-English summary
A group of 19 dogs, mostly Golden Retrievers and Rottweilers over 5 years old, were found to have bone lesions linked to a type of cancer called histiocytic sarcoma. These dogs often showed signs like limping or neurological issues, and many had soft tissue masses near the affected bones. The bone lesions were aggressive and commonly affected areas like the spine and joints. Unfortunately, most of the dogs had the more severe form of the disease, which can spread throughout the body. This highlights the importance of checking for histiocytic sarcoma in older dogs with unusual bone problems.
People also search for: dog bone cancer symptoms · Rottweiler lameness treatment · Golden Retriever cancer signs
Abstract
The purpose of this study was to describe the clinical and radiographic findings in dogs with bone lesions secondary to histiocytic sarcoma. Nineteen dogs with radiographically identified bone lesions that were histologically diagnosed as histiocytic sarcoma were assessed. The medical records, all available radiographs and histologic sections were reviewed retrospectively. Dogs were subcategorized into localized or disseminated histiocytic sarcoma groups. Golden Retrievers or Rottweilers greater than 5 years of age, with a history of lameness or neurologic deficits localized to the spinal cord was the most common presentation. Fifteen of 19 dogs had a radiographically detectable soft tissue mass associated with bone destruction. The bone lesions had aggressive characteristics and the sites of involvement included periarticular bones (n = 11), vertebrae (n = 6), proximal humerus (n = 5), and rib (n = 2). Fifteen of 19 dogs had disseminated histiocytic sarcoma, and four had localized histiocytic sarcoma. All Rottweilers had disseminated histiocytic sarcoma. Histiocytic sarcoma should be considered as a differential diagnosis for aggressive periarticular, vertebral, or proximal humeral bone lesions identified on radiographs. The index of suspicion should be increased in greater than 5-year-old Golden Retrievers and Rottweilers when a soft tissue mass is associated with the bone lesion on radiographs or myelography. Bone involvement with histiocytic sarcoma, and the Rottweiler breed, was associated with the disseminated form of the disease.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18018725/