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Peer-reviewed veterinary case report

Dog with persistent diarrhea and vomiting

By Paris, J K et al.·Published in Journal of comparative pathology·2013·Royal (Dick) School of Veterinary Studies and Roslin Institute, United Kingdom·View original on PubMed

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Original publication title: Small intestinal ganglioneuromatosis in a dog.

Species:
dog

Plain-English summary

A 9-year-old female collie-cross was brought to the vet with ongoing diarrhea, weight loss, and occasional vomiting for two months. An ultrasound showed a thickened section of her small intestine, leading to surgery where the affected part was biopsied and removed. The diagnosis was small intestinal ganglioneuromatosis, a rare condition. After the surgery, the dog recovered well, her diarrhea stopped, and she gained weight, remaining healthy eleven months later.

People also search for: dog diarrhea weight loss treatment · collie-cross vomiting · small intestinal ganglioneuromatosis in dogs

Abstract

A 9-year-old female neutered collie-cross dog was presented with a 2-month history of persistent diarrhoea, weight loss and intermittent vomiting. Abdominal ultrasonography revealed one loop of jejunum with a markedly thickened and multifocally hyperechoic wall, without loss of wall layering. Laparotomies were performed for biopsy and resection of affected intestine. Histopathological examination revealed small intestinal ganglioneuromatosis (GN). The dog recovered well from surgery and the diarrhoea resolved. Eleven months later the dog has gained weight and remains asymptomatic. This is the first report of small intestinal GN affecting a mature dog, in which pathology was localized to the mucosal lamina propria and surgical treatment resulted in a successful outcome.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22925263/