Peer-reviewed veterinary case report
Dog with larynx tumor treated successfully with chemo
By Hayes, A M et al.·Published in The Journal of small animal practice·2007·Animal Health Trust·View original on PubMed →
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Original publication title: Solitary extramedullary plasmacytoma of the canine larynx.
- Species:
- dog
Plain-English summary
An 11-year-old female spayed cocker spaniel was brought in because she had trouble making sounds (dysphonia) due to a mass in her larynx. After a biopsy, the mass was identified as a plasmacytoma, a type of tumor. While radiation therapy didn't work, a combination of chemotherapy treatments successfully kept the tumor at bay. Now, 30 months after her diagnosis, the dog is still free of the disease and doing well.
People also search for: dog laryngeal tumor treatment · cocker spaniel dysphonia · plasmacytoma in dogs · chemotherapy for dog tumors
Abstract
An 11-year-old, female, spayed cocker spaniel was presented with dysphonia caused by a solitary laryngeal mass. Excisional biopsy was performed, and a diagnosis of plasmacytoma was made on the basis of histological examination. Further investigations showed no signs of systemic involvement. Coarse fractionated radiation therapy failed to control the tumour. Therapy was successfully instituted with a conventional combination chemotherapy protocol over a period of 14 months. The dog remains disease free 30 months after diagnosis. Most solitary, extramedullary plasmacytomas in dogs arise in the gastrointestinal tract, with fewer reports in other sites. The larynx is an uncommon sight of involvement in any species, and to the authors' knowledge, this is the first report of this tumour type in the canine larynx. In contrast to the therapeutic benefits reported in humans, the combination of surgery and radiation therapy was unsuccessful in this case, although sustained remission was gained following chemotherapy.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17425696/