Peer-reviewed veterinary case report
Soy isoflavone equol perpetuates dextran sulfate sodium-induced acute colitis in mice.
- Journal:
- Bioscience, biotechnology, and biochemistry
- Year:
- 2011
- Authors:
- Sakai, Tohru et al.
- Affiliation:
- Department of Public Health and Applied Nutrition · Japan
- Species:
- rodent
Abstract
The effects of the soy isoflavones, genistein, daidzein and equol, on experimental colitis were examined. Equol severely perpetrated dextran sulfate sodium (DSS)-induced colitis as evaluated by the weight loss. Production of the anti-inflammatory cytokine, IL-10, from T cells was decreased in the equol-treated mice. The results show that the soy isoflavone, equol, played an important role in the inflammatory response in the gastrointestinal tract.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/21389602/