Peer-reviewed veterinary case report
Spatial Profiling of Germinal Centers in Mouse Secondary Lymphoid Organs Using MACSima Imaging Cyclic Staining Technology.
- Year:
- 2026
- Authors:
- Molina ISM et al.
- Affiliation:
- Babraham Institute · United Kingdom
Abstract
We developed a 50-plex imaging protocol using the MACSima platform to characterize the microarchitecture of germinal centers in secondary lymphoid tissues. This workflow combines tissue processing, automated cyclic imaging, image preprocessing, and a new analysis method that detects morphological changes in irregularly shaped stromal cells.
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Search related cases →Original publication: https://europepmc.org/article/MED/41732996