Peer-reviewed veterinary case report
New lipid extract collar helps dogs with atopic dermatitis
By Segarra, Sergi et al.·Published in Veterinary Sciences·2023·R&D Bioiberica S.A.U., Avinguda dels Països Catalans, 34, 08950 Esplugues de Llobregat, Spain, Spain·View original on Crossref →
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Original publication title: Sphingomyelin-Rich Lipid Extract Collar for Canine Atopic Dermatitis
- Species:
- dog
Plain-English summary
A group of dogs with atopic dermatitis (a skin allergy) were tested with a new collar containing a special lipid extract designed to improve skin health. Over eight weeks, the dogs showed significant improvement in their skin condition and itching without any side effects. This collar could be used alongside other treatments, potentially making it easier for owners to manage their pets' allergies while reducing the need for medications.
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Abstract
The management of canine atopic dermatitis (CAD) is complex, and it needs to be multimodal, combining topical and systemic therapies. Given that the currently available options are not always totally effective and might have some associated adverse effects, novel alternatives are needed. For this reason, a new collar for CAD was developed with 2.5% of a sphingomyelin-rich lipid extract (LE) with proven benefits for skin health. The release of the active ingredient when incorporated into the collar was tested in vitro, showing an adequate kinetic profile. Then, the efficacy and safety of the collar were assessed in 12 client-owned dogs with CAD in a pilot study. After eight weeks, the dogs experienced significant clinical improvements on the Canine Atopic Dermatitis Extent and Severity Index (CADESI)-4, Pruritus Index for Canine Atopic Dermatitis (PCAD) and Pruritus Visual Analogue Scale (PVAS) scores, without any adverse effects. Additionally, further in vitro studies were performed, indicating that this LE collar should be compatible with antiparasitic collars (with deltamethrin or imidacloprid/flumethrin) if worn simultaneously. Given the observed benefits of this LE collar, combining it with other CAD therapies could potentially allow for drug sparing, reduction in adverse effects, enhanced owner compliance, and reduced treatment costs.
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Search related cases →Original publication on Crossref: https://doi.org/10.3390/vetsci10060389