Peer-reviewed veterinary case report
Lump behind left lower molar in 13-year-old Labrador dog was spindle
By Hatai, Hitoshi et al.·Published in The Journal of veterinary medical science·2013·School of Veterinary Medicine, Japan·View original on PubMed →
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Original publication title: Spindle cell ameloblastic carcinoma in a labrador retriever dog.
- Species:
- dog
Plain-English summary
A 13-year-old male Labrador retriever was brought to the vet with a mass near his back left molar. After the tumor was surgically removed, it unfortunately came back just a month later, requiring another surgery. The tumors were diagnosed as spindle cell ameloblastic carcinoma, which is a type of cancer that can grow aggressively. The vet was able to remove both tumors, but pet owners should be aware that this type of cancer can recur, so regular check-ups are important.
People also search for: Labrador retriever mouth tumor · dog cancer treatment · recurrent tumor in dogs
Abstract
A 13-year-old castrated male Labrador retriever dog presented with a mass caudal to the first molar of his left mandible. Although the tumor was excised, a recurrent tumor was detected one month later and resected. Both tumors displayed invasive growth and were composed of neoplastic proliferation arranged in irregular lobules, nests and cords continuous with mucosal epithelium. The most prominent feature of the tumors was the presence of many proliferating spindle cells admixed with palisading basal-like cells, acanthocytes and stellate cells. In immunohistochemical examinations, the spindle cells were found to be positive for vimentin; cytokeratin AE1/AE3, 5/6, 14 and 19; and p63. The other neoplastic cells were positive for all of these markers shown above except vimentin. Based on these findings, the tumors were diagnosed as spindle cell ameloblastic carcinoma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23229541/