Peer-reviewed veterinary case report
Cat with bone infection and Splendore-Hoeppli reaction
By França, Silvia de Araujo et al.·Published in Journal of feline medicine and surgery·2014·Departamento de Clinica e Cirurgia, Brazil·View original on PubMed →
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Original publication title: Splendore-Hoeppli phenomenon in a cat with osteomyelitis caused by Streptococcus species.
- Species:
- cat
Plain-English summary
A 9-month-old male neutered mixed-breed cat was brought in for chronic limping on his right hind leg that didn't get better with antibiotics. X-rays showed severe bone damage, indicating osteomyelitis (a bone infection). Despite surgery and more antibiotics, his condition didn't improve, leading to the decision to amputate the leg. After the amputation, tests confirmed the infection was caused by Streptococcus bacteria. The cat's recovery was closely monitored following the surgery.
People also search for: cat limping treatment · cat osteomyelitis symptoms · Streptococcus infection in cats · cat leg amputation recovery
Abstract
A 9-month-old male neutered mixed-breed cat had a history of chronic lameness of the right hind limb, which was non-responsive to antibiotic treatment. Hematologic analysis revealed marked neutrophilia and mild monocytosis. Radiography revealed extensive loss of cortical bone, and replacement with irregular and disorganized bone. There was loss of the normal cortico-medullary distinction, and the medullary cavity had an irregular radiodensity suggestive of osteomyelitis. Surgical curettage and antibiotics did not improve the clinical condition, and amputation was performed. Grossly, the skin over the right tibia was ulcerated with a viscous and granular exudate. At histopathology, there was marked diffuse pyogranulomatous dermatitis, myositis, periostitis and osteomyelitis associated with Splendore-Hoeppli phenomenon. In addition, there was marrow osteoproliferation and multifocal cortical loss, reabsorption, fibroplasia and endosteal bone formation. Gram staining revealed myriad slightly elongated Gram-positive bacteria, arranged in pairs or single chains, confirmed by polymerase chain reaction as Streptococcus species.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23906707/