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Peer-reviewed veterinary case report

Alaskan Malamute with spleen tumor, high blood pressure

By Kim, Jung-Hyun et al.·Published in BMC veterinary research·2018·Department of Veterinary Internal Medicine, South Korea·View original on PubMed

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Original publication title: Splenic malignant fibrous histiocytoma with concurrent hypertension and epistaxis in an Alaskan malamute dog.

Species:
dog

Plain-English summary

A 10-year-old Alaskan Malamute was brought in with severe nosebleeds that lasted for five days and high blood pressure. After tests showed a large mass in the spleen, the dog underwent surgery to remove the spleen. Following the surgery, both the nosebleeds and high blood pressure improved and did not return during a follow-up five months later. This case suggests that nosebleeds and high blood pressure can be linked to a rare type of tumor in dogs.

People also search for: dog nosebleed causes · Alaskan Malamute high blood pressure treatment · malignant fibrous histiocytoma in dogs

Abstract

BACKGROUND: Malignant fibrous histiocytoma has been uncommonly described in dogs. Several extranasal neoplasias have been reported to result hypertensive epistaxis. There are, however, no published case reports of extranasal malignant fibrous histiocytoma with concurrent hypertension and epistaxis in dogs. CASE PRESENTATION: A 10-year-old dog presented with a spontaneous massive epistaxis persisting for 5 days. The dog exhibited unstable hypertension, which was considered as a cause of epistaxis. The complete blood count, prothrombin time, and activated partial thromboplastin time were within the reference limits, and other systemic examination showed no abnormalities except for a splenic mass occupying more than one third of the abdomen. Histologic examination of the resected spleen revealed the characteristic features of a malignant fibrous histiocytoma. One week after splenectomy, the hypertension and epistaxis resolved clinically and did not recur on the 5-month follow-up. CONCLUSIONS: The dog's blood pressure and epistaxis normalized after malignant fibrous histiocytoma resection suggesting that hypertensive epistaxis may be a rare manifestation of canine malignant fibrous histiocytoma.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30103739/