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Peer-reviewed veterinary case report

Dog's diabetes went away after pancreatitis treatment

By Claude, Riley et al.·Published in Journal of veterinary internal medicine·2026·Department of Small Animal Clinical Sciences, United States·View original on PubMed

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Original publication title: Spontaneous diabetic remission after acute pancreatitis in a dog.

Species:
dog

Plain-English summary

A 7-year-old spayed female mixed-breed dog developed diabetes after suffering from acute pancreatitis. She was treated with insulin injections twice a day for two months, but her vet stopped the treatment after she showed signs of low blood sugar and her glucose levels remained normal. Remarkably, 19 months later, the dog continued to have normal blood sugar levels without any insulin, indicating a rare diabetic remission. This case shows that even dogs with diabetes related to pancreatitis can sometimes recover fully.

People also search for: dog diabetes treatment · pancreatitis in dogs · signs of low blood sugar in dogs

Abstract

A 7-year-old spayed female mixed-breed dog was diagnosed with acute pancreatitis and received supportive care for 2 weeks, after which the dog developed diabetes mellitus (DM). Insulin therapy was initiated (insulin glargine 300 U/ml) at 0.2 U/kg subcutaneously (SQ) every 12 hours with no dose adjustments required. After 2 months, insulin therapy was discontinued because of a suspected hypoglycemic episode and persistently normal interstitial glucose concentrations. Nineteen months after diagnosis, the dog remained euglycemic with normal hemoglobin A1c, consistent with diabetic remission. Diabetic remission is rare in dogs and is reported only in the context of insulin-resistance caused by excess progesterone or glucocorticoids and in a single case report with no obvious cause of insulin-resistance. The case reported here demonstrates that even in pancreatitis-related DM, remission is possible in a dog.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/41742530/