Peer-reviewed veterinary case report
Dogs sneezing up lumps from nose or mouth - study of 21 cases
By Pineda, Daniel A Sebastian et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2025·Department of Pathology, United States·View original on PubMed →
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Original publication title: Spontaneous oronasal ejection of neoplastic and non-neoplastic nodules by 21 dogs, 2000-2024.
- Species:
- dog
Plain-English summary
A group of 21 adult dogs experienced unusual symptoms, including sneezing and nosebleeds, and some even expelled fleshy nodules from their mouths or noses. These nodules were examined and found to be mostly tumors, including various types of cancers. The dogs were treated based on the specific type of tumor identified, which could help guide further care. This case highlights the importance of investigating any unusual tissue ejection in pets, as it can provide valuable information for diagnosis and treatment.
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Abstract
Spontaneous ejection of tissues from body orifices is rare in veterinary medicine. Here we underscore the diagnostic value of tissues spontaneously ejected from the nose or mouth of 21 dogs and submitted for histologic evaluation at 3 veterinary diagnostic institutions. Cases were retrospectively searched (2000-2024) from the Athens Veterinary Diagnostic Laboratory, Tifton Veterinary Diagnostic and Investigational Laboratory, and Antech Diagnostics web-based archive systems. Affected dogs were adults (x̄ age = 9.5 y) of several breeds. There were 13 male (8 castrated, 5 intact) and 8 spayed female dogs. Clinical signs consisted mainly of sneezing (19 of 21 cases) and epistaxis (11 cases), with spontaneous ejection of red-to-brown and fleshy-or-spongy nodules from the nose (19 cases) or mouth (2). Histologically, lesions consisted of neoplasms (19 cases) or clusters of fibrinous or suppurative exudate with hemorrhage (2). Epithelial neoplasms consisted of carcinomas and adenocarcinomas (3 cases each), and squamous cell carcinoma and a presumed adenoma (1 case each). Mesenchymal neoplasms consisted of spindle-cell sarcomas (4 cases), presumed osteosarcomas (2), and a chondrosarcoma and a chondrosarcoma/chondroblastic osteosarcoma (1 case each). Round-cell neoplasms included a B-cell lymphoma, a presumed lymphoma, and a plasmacytoma (1 case each). The presence of nasal mucosa and turbinates was supportive of nasal tumor in 4 cases. Although the anatomic origin of neoplasms cannot be determined in all cases, tissues ejected from the nose or mouth can be suitable for a histologic diagnosis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/40905166/