Peer-reviewed veterinary case report
Dog footpad warts from papillomavirus that went away on their own
By Iyori, Keita et al.·Published in The Journal of veterinary medical science·2019·Vet Derm Tokyo, Japan·View original on PubMed →
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Original publication title: Spontaneous regression of canine papillomavirus type 2-related papillomatosis on footpads in a dog.
- Species:
- dog
Plain-English summary
A 9-year-old male French bulldog had cauliflower-like growths on the footpads of his left front leg due to an infection with canine papillomavirus type 2 (CPV-2). After a biopsy to examine the lesions, the growths surprisingly started to shrink on their own without any specific treatment. This suggests that in healthy dogs, CPV-2-related papillomatosis can sometimes resolve naturally after a biopsy. If your dog has similar symptoms, it might be worth discussing this possibility with your veterinarian.
People also search for: dog footpad growths · French bulldog papillomavirus · dog skin lesions treatment
Abstract
Persistent papillomatosis on footpads related to canine papillomavirus type 2 (CPV-2) infection has been described in dogs with immunocompromised condition. A 9-year-old, male French bulldog was presented with cauliflower-like nodules on the footpads of his left front leg. Histopathological examination revealed multiple finger-like projections of squamous epithelium with intranuclear inclusion bodies. Immunohistochemistry using an anti-bovine papillomavirus antibody demonstrated immunostaining in the keratinocytes. Partial genome DNA of CPV-2 was amplified from the lesion. Full genome sequence of CPV-2 in the subject showed 99.95% nucleotide identity with that of CPV-2 from the reference data. Two weeks after a biopsy, the skin lesion spontaneously regressed without any specific treatment. In non-immunocompromised dogs, CPV-2-related footpad papillomatosis could spontaneously resolve after a biopsy.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31105085/