Peer-reviewed veterinary case report
Extra islet pancreas cell growth in young Beagle dogs
By Son, Woo-Chan et al.·Published in Toxicology letters·2010·Department of Pathology, United Kingdom·View original on PubMed →
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Original publication title: Spontaneously occurring extra-islet endocrine cell proliferation in the pancreas of young Beagle dogs.
- Species:
- dog
Plain-English summary
A group of young Beagle dogs was found to have unusual growths in their pancreas, which involved an increase in certain types of cells. This condition, similar to what is seen in human infants, was observed more frequently and severely in younger dogs. Despite these changes, the dogs' blood sugar levels remained normal, indicating that their insulin function was not affected. The findings suggest that while these growths are present, they may not pose an immediate health risk.
People also search for: Beagle dog pancreas problems · young dog pancreatic issues · Beagle nesidioblastosis symptoms
Abstract
Pancreas of Beagle dogs deriving from 166 male and 166 female animals were examined microscopically and were found to show nesidioblastosis-like structural alteration in 29 dogs. The lesion was represented by endocrine and ductular epithelial cell proliferation. The incidence profile and the severity of the changes observed were closely associated with the age of the dogs, younger dogs being more often and more seriously affected than older dogs. No link with altered insulin function has been established as serum glucose levels were found to be within the normal range. The pathology of spontaneous extra-islet endocrine cell proliferation in the young Beagle dogs, described in this study, has some similarities to that of nesidioblastosis of human neonates and infants.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20083172/