Peer-reviewed veterinary case report
Squamous cell anal sac cancer in five dogs and outcomes
By Esplin, D G et al.·Published in Veterinary pathology·2003·Animal Reference Pathology Division, United States·View original on PubMed →
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Original publication title: Squamous cell carcinoma of the anal sac in five dogs.
- Species:
- dog
Plain-English summary
Five dogs were diagnosed with squamous cell carcinoma, a type of cancer that developed in the lining of their anal sacs. This condition is rare compared to other tumors in the perianal area. Unfortunately, four of the dogs had to be euthanized due to complications from the tumors invading surrounding tissues. The fifth dog underwent surgery to remove the tumor and showed no signs of cancer seven months later, but there was no further follow-up on its condition.
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Abstract
Tumors of the perianal area of dogs are common and include multiple tumor types. Whereas perianal adenomas occur often, adenocarcinomas of the apocrine glands of the anal sac occur less frequently. A review of the literature revealed no reports of squamous cell carcinomas arising from the epithelial lining of the anal sac. Squamous cell carcinomas originating from the lining of the anal sac were diagnosed in five dogs. Microscopically, the tumors consisted of variably sized invasive nests and cords of epithelial cells displaying squamous differentiation. Four of the five dogs were euthanatized because of problems associated with local infiltration by the tumors. In the fifth dog, there was no evidence of tumor 7 months after surgical removal, but further follow up was not available.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/12724576/