Peer-reviewed veterinary case report
Dog with kidney squamous cell cancer that spread to lungs
By Dagli, M L et al.·Published in Journal of comparative pathology·1997·Department of Pathology, Brazil·View original on PubMed →
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Original publication title: Squamous cell carcinoma of the renal pelvis with metastasis in a dog.
- Species:
- dog
Plain-English summary
An 18-year-old dog was found to have a rare type of cancer called squamous cell carcinoma in the renal pelvis, which is the area of the kidney that collects urine. Unfortunately, this tumor had spread to other parts of the body, including the lungs and small intestine, and was only discovered during a necropsy after the dog passed away. The cancer likely developed due to changes in the cells caused by kidney stones. Sadly, there was no treatment since the diagnosis was made post-mortem.
People also search for: dog kidney cancer symptoms · squamous cell carcinoma in dogs · dog cancer treatment options
Abstract
The gross and microscopical features of a squamous cell carcinoma of the renal pelvis in an 18-year-old dog are described. This is a rare tumour originating from transitional cells of the pelvis. The tumour, which invaded the renal parenchyma and capsule and the small intestinal wall, metastasized to the lungs. Tumour cells expressed cytokeratin 8 and were arranged in a pattern similar to that of a squamous cell carcinoma found elsewhere, with prickle cells and horny pearls. The tumour was not diagnosed clinically but was found at necropsy. The presence of pelvic calculi in this dog is suggested as a cause of transitional cell squamous metaplasia and malignant transformation.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/9179752/