Peer-reviewed veterinary case report
Dog with nasal discharge diagnosed with rare nasal cancer type
By Bosward, K L et al.·Published in Australian veterinary journal·2004·Faculty of Veterinary Science, United Kingdom·View original on PubMed →
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Original publication title: Squamous cell carcinoma with sarcomatous stroma in the nasal cavity of a dog.
- Species:
- dog
Plain-English summary
A 13-year-old Golden Retriever was brought in with a runny nose and eye discharge that only got worse over time. Despite tests, the vet couldn't find the cause, and sadly, the dog was euthanized when symptoms worsened. A post-mortem examination revealed a nasal tumor made up of squamous cell carcinoma, which is a type of skin cancer, along with other abnormal cells. This case highlights the challenges in diagnosing certain types of tumors in dogs, especially when symptoms are vague.
People also search for: dog nasal discharge · Golden Retriever tumor symptoms · dog cancer diagnosis · nasal tumor in dogs · squamous cell carcinoma in dogs
Abstract
This is a report of an unusual squamous cell carcinoma in the nasal cavity of a dog. A 13-year-old Golden Retriever was presented with a unilateral nasal and ocular discharge. Although a nasal tumour was suspected, initial diagnostic investigations were unrewarding, and, with worsening clinical signs, the dog was euthanatized. Necropsy examination confirmed the presence of a nasal tumour that was composed histologically of both a well-differentiated squamous cell carcinoma component blending with a predominant spindle cell component. Immunohistochemical staining with anti-human keratin/cytokeratin (AE1/AE3, CAM 5.2 and broad spectrum cytokeratin), Vimentin, Desmin, smooth muscle actin and S-100 protein supported a diagnosis of a squamous cell carcinoma with (pseudo) sarcomatous stroma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15481108/