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Peer-reviewed veterinary case report

Sry-negative XX sex reversal in a French Bulldog.

Journal:
Reproduction in domestic animals = Zuchthygiene
Year:
2011
Authors:
Campos, M et al.
Affiliation:
Universidad CEU-Cardenal Herrera · Spain
Species:
dog

Abstract

Here, we describe a 3-month-old XX male French Bulldog. The diagnosis was based on the clinical signs, gonadal histology and cytogenetic analysis. Additionally, the dog was confirmed to be Sry negative by semi-quantitative reverse transcription polymerase chain reaction (sqRT-PCR). Canine Sry-negative XX sex reversal is a disorder of gonadal development where individuals who have a female karyotype develop testes or ovotestes. To our knowledge, this case is the first XX male sex reversion described in a French Bulldog.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/20412513/