Peer-reviewed veterinary case report
French Bulldog puppy with Sry-negative XX male sex reversal
By Campos, M et al.·Published in Reproduction in domestic animals = Zuchthygiene·2011·Universidad CEU-Cardenal Herrera, Spain·View original on PubMed →
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Original publication title: Sry-negative XX sex reversal in a French Bulldog.
- Species:
- dog
Plain-English summary
A 3-month-old male French Bulldog was found to have a rare condition called XX sex reversal, where a dog with a female genetic makeup develops male reproductive organs. This was confirmed through various tests, including a genetic analysis. The dog showed signs typical of this condition, which can affect how the reproductive system develops. This case is notable as it's the first documented instance of this condition in a French Bulldog.
People also search for: French Bulldog male reproductive issues · XX sex reversal in dogs · dog with female genetics · canine reproductive disorders
Abstract
Here, we describe a 3-month-old XX male French Bulldog. The diagnosis was based on the clinical signs, gonadal histology and cytogenetic analysis. Additionally, the dog was confirmed to be Sry negative by semi-quantitative reverse transcription polymerase chain reaction (sqRT-PCR). Canine Sry-negative XX sex reversal is a disorder of gonadal development where individuals who have a female karyotype develop testes or ovotestes. To our knowledge, this case is the first XX male sex reversion described in a French Bulldog.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20412513/