Peer-reviewed veterinary case report
Female English Cocker Spaniel with male sex traits and no heat cycle
By D. Nak et al.·Published in Veterinární Medicína·2015·Faculty of Veterinary Medicine, Uludag University, Bursa, Turkey, CZ·View original on DOAJ →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: SRY-negative XX sex reversal in an English Cocker Spaniel: a case report
- Species:
- dog
Plain-English summary
A one-year-old English Cocker Spaniel was brought to the vet because she had not gone into heat, which is unusual for female dogs. Upon examination, the vet found an enlarged clitoris and performed surgery to investigate further. During the surgery, they discovered that instead of ovaries, the dog had testicular tissue, even though her genetic makeup indicated she was female. The surgery confirmed the presence of two testes and a normal uterus. The dog recovered well after the procedure.
People also search for: why is my dog not going into heat · English Cocker Spaniel sex reversal · dog testicular tissue in female · gonado-hysterectomy in dogs
Abstract
A SRY-negative XX male describes a female karyotype with testicular tissue resulting from abnormal gonadal development. In such cases male gonad formation takes place in the absence of a Y chromosome which supports the hypothesis that some other genes are also responsible for testicular development. The present case report describes a one-year-old dog brought to the hospital with a complaint of no oestrus cycle. Apparently normal masculine bitch had an enlarged clitoris with an os on radiograph. A gonado-hysterectomy was performed. Instead of ovarian structures both testicular masses were present and a normal complete bicornuate uterus with a normal cervix was observed. The histology of both gonads showed two testes, each with its ductus deferens and the uterus with typical histological structure. Cytogenetic evaluation of peripheral blood lymphocytes revealed a female with a normal karyotype (78, XX). Polymerase chain reaction (PCR) analysis of genomic DNA showed that the SRY gene was absent.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on DOAJ: https://doi.org/10.17221/8064-VETMED