Peer-reviewed veterinary case report
Staphylococcus pseudintermedius from cat forms strong biofilms
By Sato, Yoshinori et al.·Published in Scientific reports·2024·Department of Microbiology and Immunology, Japan·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Staphylococcus pseudintermedius ST2660 isolated from a cat has strong biofilm-forming ability and increases biofilm formation at cat's normal body temperature.
- Species:
- cat
Plain-English summary
A cat with skin wounds from excessive grooming was treated with orbifloxacin, an antibiotic, but after 80 days, a severe abscess developed. Tests showed that the bacteria causing the infection, Staphylococcus pseudintermedius, had become resistant to the antibiotic and was able to form strong biofilms, especially at the cat's normal body temperature. This strain of bacteria was identified as a new type and had genes that made it particularly virulent. The findings highlight the challenges of treating infections in pets and the importance of monitoring for antibiotic resistance.
People also search for: cat skin infection treatment · antibiotic resistance in cats · why is my cat grooming excessively
Abstract
Staphylococcus pseudintermedius has been isolated from dogs, cats, and horses and is also known as an emergent zoonotic agent. We administered orbifloxacin, a fluoroquinolone, to treat bacterial infections of cutaneous wounds caused by excessive grooming of the skin in contact with the subcutaneous port of the subcutaneous ureteral bypass (SUB) system in a cat. However, after 80 days of treatment, a severe abscess was observed in the wound and fluoroquinolone-resistant S. pseudintermedius was isolated from the abscess. The isolate was identified as a novel sequence type (ST) 2660 and contained genes for leukocidins (lukS and lukF), exfoliative toxin (siet), and biofilm regulation (icaA and icaD). The isolate was resistant to macrolide, lincosamide, fluoroquinolone, and tetracycline classes. In addition, the isolate had strong biofilm-forming ability which significantly increased with culturing at 39 °C compared with that at 37 °C, suggesting that the isolate prefers a cats' body temperature as the optimal biofilm growth condition. Notably, the biofilms were increased in the presence of doxycycline with culturing at 39 °C. This study is the first report in Japan on the new sequence type of S. pseudintermedius isolated from a companion animal and clarifies the distinctive virulence of S. pseudintermedius.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39394228/