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Peer-reviewed veterinary case report

Status epilepticus and cluster seizures in companion animals

By Patterson, Edward Ned E·Published in The Veterinary clinics of North America. Small animal practice·2014·Department of Veterinary Clinical Sciences, United States·View original on PubMed

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Original publication title: Status epilepticus and cluster seizures.

Species:
dog

Plain-English summary

Status epilepticus is a serious condition in pets where they have prolonged seizures, which can lead to significant health problems and even death. Treatment usually involves giving sedatives and anesthetics to help control the seizures. For immediate care, veterinarians often start with benzodiazepines, and if those aren't effective, they may use other medications in a step-by-step approach. Recently, a medication called levetiracetam has been used in dogs and shows promise for treating this condition. It's important to act quickly and seek veterinary help if your pet is experiencing seizures.

Abstract

Status epilepticus (SE) is a medical emergency for companion animals, with significant associated morbidity and mortality. Therapy in companion animals and people has been largely with sedatives and anesthetics, many of which have gamma-aminobutyric acid receptor-mediated mechanisms. Early aggressive treatment includes staged first-line therapy with benzodiazepines, and second- and third-line protocols when needed. Recently, intravenous levetiracetam has also been used in for SE in dogs and people, and there are other human intravenous drug preparations that may hold promise for future use in companion animals.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/25245182/