Peer-reviewed veterinary case report
Stem cell therapy for necrotizing enterocolitis: innovative techniques and procedures for pediatric translational research.
- Journal:
- Methods in molecular biology (Clifton, N.J.)
- Year:
- 2014
- Authors:
- Yang, Jixin et al.
- Affiliation:
- Department of Pediatric Surgery · China
- Species:
- rodent
Abstract
Necrotizing enterocolitis (NEC) is the most common gastrointestinal emergency of newborns, especially those born prematurely. Mesenchymal stem cell (MSC) therapy has shown efficacy in protection against various forms of tissue injury, and we have demonstrated efficacy in experimental NEC. However, few studies have been performed to establish a safe and effective method of intravenous MSC infusion for newborns. Here we described a safe, non-traumatic, and effective technique for systemic MSC transplantation in newborn rats.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/25173379/