Peer-reviewed veterinary case report
Radiation treatment outcomes for brain tumors in dogs
By Griffin, L.R. et al.·Published in Veterinary and Comparative Oncology·2014·Department of Environmental and Biological Health Sciences, Colorado State University Fort Collins CO USA, United States·View original on Crossref →
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Original publication title: Stereotactic radiation therapy for treatment of canine intracranial meningiomas
- Species:
- dog
Plain-English summary
A group of dogs with brain tumors called meningiomas underwent stereotactic radiation therapy (SRT) to treat their condition. After treatment, some dogs experienced a temporary worsening of their neurological symptoms, which was managed with corticosteroids, leading to improvement in most cases. On average, dogs survived about 561 days after treatment, but 13% passed away within six months due to worsening symptoms. The amount of healthy brain tissue exposed to radiation was linked to a higher risk of these complications.
People also search for: dog brain tumor treatment · canine meningioma symptoms · stereotactic radiation therapy for dogs
Abstract
AbstractThe objective of this study is to determine the rate of toxicity, median survival time (MST) and prognostic factors in dogs with presumed intracranial meningiomas that were treated with stereotactic radiation therapy (SRT). Patient demographics, neurological history, details ofSRTplans and response to treatment (including toxicity and survival times) were examined for potential prognostic factors. Overall MST (MST) due to death for any cause was 561 days. There was a mild to moderate exacerbation of neurological symptoms 3‐16 weeks followingSRTtreatments in 11/30 (36.7%) of dogs. This presumed adverse event was treated with corticosteroids, and improvement was seen in most of these dogs. Death within 6 months of treatment as a result of worsening neurologic signs was seen in 4/30 (13.3%) of dogs. Volume of normal brain that received full dose at a prescription of8Gy× 3 fractions was predictive of death due to neurological problems within this 6‐month period.
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Search related cases →Original publication on Crossref: https://doi.org/10.1111/vco.12129