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Peer-reviewed veterinary case report

Cat with firm skin lump treated for sterile nodular panniculitis

By A. Silvio Neto et al.·Published in Arquivo Brasileiro de Medicina Veterinária e Zootecnia·2025·View original on DOAJ

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Original publication title: Sterile pyogranulomatous nodular panniculitis in a cat - case report

Species:
cat

Plain-English summary

A 1-year-old male mixed-breed cat was brought to the vet with a single, ulcerated, red nodule on its skin. After running several tests, including blood work and a biopsy, the vet diagnosed the cat with a rare inflammatory condition called sterile nodular pyogranulomatous panniculitis. The treatment involved giving the cat prednisolone, a steroid, and dipyrone for pain relief. Fortunately, the cat responded well to the treatment, and the nodule completely healed.

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Abstract

ABSTRACT Sterile nodular pyogranulomatous panniculitis is an inflammatory disease of variable extent and severity, considered uncommon in dogs and rare in felines. The aim of this study was to report the case of a feline with sterile nodular pyogranulomatous panniculitis responsive to pharmacological treatment. A male, mixed breed cat, weighing 4 kg, aged one year, was treated with a history of a single, ulcerated, erythematous, slightly irregular and firm nodule. Complete blood count, biochemical tests, cytology of the nodule, culture, radiography and histopathology were requested. The definitive diagnosis was obtained through histopathological examination and the established treatment, with prednisolone at a dose of 1 mg/kg, BID, for the first ten days, subsequently reduced to SID for another 10 days, associated with dipyrone 1 drop/kg, BID, for 5 days, was sufficient for the remission of the lesion. It is concluded that Sterile nodular pyogranulomatous panniculitis is a rare disease in felines, but important considering the wide diversity of differential diagnoses, and that in the case of a single nodular presentation, clinical treatment was sufficient for complete remission, and histopathology was the determining exam for diagnostic confirmation.

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Original publication on DOAJ: https://doi.org/10.1590/1678-4162-13413